Endothelial dysfunction occurs when the endothelium, the thin layer of cells lining blood vessels, fails to perform its normal functions. This can disrupt blood flow and lead to various cardiovascular problems. It is often associated with conditions such as high blood pressure, diabetes, and high cholesterol, and can be a sign of early heart disease.
Understanding endothelial dysfunction is important because it plays a significant role in heart health. When the endothelium does not function correctly, it can contribute to the development of atherosclerosis, which is the buildup of fatty deposits in the arteries. This can increase the risk of heart attacks and strokes, making it a critical area of concern for overall cardiovascular health.
The endothelium has several key functions in the body, including regulating blood flow, maintaining blood vessel tone, and preventing blood clotting. It helps control the movement of substances and white blood cells into and out of the bloodstream. When the endothelial cells are healthy, they help to keep blood vessels open and functioning well, which is essential for delivering oxygen and nutrients to tissues.
Recognizing endothelial dysfunction is important for early intervention and management of cardiovascular diseases. Monitoring heart health and understanding the factors that can affect the endothelium can lead to better outcomes for individuals at risk for heart-related issues.