IgA

Definition:IgA is an antibody that plays a key role in protecting mucosal surfaces in the body.
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IgA is the immune system’s front-line antibody for mucosal surfaces like the gut, airways, and genitourinary tract. This guide explains how IgA works, what “low” or “high” IgA can mean, how IgA is tested, and practical ways to support mucosal immunity while understanding real-world risks.

IgA, or Immunoglobulin A, is a type of antibody found primarily in mucosal areas, including the gut, respiratory tract, and saliva. It is one of the five main classes of antibodies produced by the immune system and is crucial for our body’s defense against infections. IgA helps to prevent pathogens, such as bacteria and viruses, from entering the body through these mucosal surfaces.

IgA is important for overall health because it provides a first line of defense against harmful microorganisms. It is especially vital in protecting areas that are exposed to the outside environment, such as the intestines and respiratory system. By keeping these pathways clear of pathogens, IgA helps to reduce the risk of infections and maintain a healthy immune response.

In the body, IgA functions by binding to pathogens and neutralizing them, which prevents them from causing harm. It also plays a role in immune memory, helping the body recognize and respond more effectively to previously encountered pathogens. IgA can be found in secretions like tears, breast milk, and mucus, which means it is actively involved in both local and systemic immunity.

Overall, IgA is a crucial component of the immune system, ensuring that mucosal surfaces remain protected and function properly. Its presence is especially noted in the immune response of infants through breast milk, which contains high levels of IgA to support their developing immune systems.

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