Insulin Resistance

Definition:Insulin resistance is when the body's cells don't respond well to insulin.
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Insulin resistance happens when your cells respond poorly to insulin, forcing your body to make more to keep blood sugar stable. Over time, this can drive weight gain, fatty liver, high triglycerides, elevated blood pressure, and progression toward prediabetes and type 2 diabetes. This guide explains the biology, the real-world signs and labs, and the most effective, evidence-based ways to improve insulin sensitivity.

Insulin resistance is a condition where the body's cells become less sensitive to the hormone insulin. Insulin helps cells absorb glucose from the blood to use as energy. When cells resist insulin, it becomes harder for glucose to enter them, leading to higher blood sugar levels.

This condition is important for health because it can lead to prediabetes and type 2 diabetes if not managed. High blood sugar levels over time can cause damage to various organs and increase the risk of heart disease and other health problems.

In the body, insulin is produced by the pancreas. When you eat, insulin helps move sugar from the bloodstream into the cells, where it's used for energy. If the cells don't respond properly, the pancreas produces more insulin to try to get the cells to take in glucose, which can eventually wear out the pancreas.

If you notice symptoms like increased thirst, frequent urination, or unexplained fatigue, it might be helpful to learn more about insulin resistance. A healthcare provider can offer advice and testing if needed.

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